Getting Started, Last Modified on June 14, 2022, Permalink
Single Cell 5' CRISPR Screening (also referred to as 5' CRISPR) enables whole transcriptome readouts for gene perturbations, along with cell surface protein and immune receptor sequences, all from the same single cell.
10x Solution | TCR/Ig | Gene Expression | Cell Surface Marker | TCR-Antigen Specificity | CRISPR |
---|---|---|---|---|---|
Single Cell Immune Profiling | ✓ | ✓ | - | - | - |
Single Cell Immune Profiling with Cell Surface Protein | ✓ | ✓ | ✓ | ✓ | - |
Single Cell Immune Profiling with CRISPR screening | ✓ | ✓ | - | - | ✓ |
Single Cell Immune Profiling with Cell Surface Protein & CRISPR | ✓ | ✓ | ✓ | - | ✓ |